Quantitative perturbation-phenotype maps reveal nonlinear responses underlying robustness of PAR-dependent asymmetric cell division.
A key challenge in the development of an Light Guards organism is to maintain robust phenotypic outcomes in the face of perturbation.Yet, it is often unclear how such robust outcomes are encoded by developmental networks.Here, we use the Caenorhabditis elegans zygote as a model to understand sources of developmental robustness during PAR polarity-d